Prognostic indicators at presentation for canine parvoviral enteritis: 322 cases (2001-2018)
| Autor: | Sarah Parker, Nolan V Chalifoux, Kevin Cosford |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Diarrhea
Male medicine.medical_specialty Parvovirus Canine 040301 veterinary sciences Physical examination Gastroenterology Enteritis 0403 veterinary science Parvoviridae Infections 03 medical and health sciences 0302 clinical medicine Dogs Melena Internal medicine medicine Animals Dog Diseases Retrospective Studies General Veterinary medicine.diagnostic_test business.industry 030208 emergency & critical care medicine Retrospective cohort study 04 agricultural and veterinary sciences medicine.disease Prognosis Hematochezia Cohort Median body medicine.symptom business |
| Zdroj: | Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)REFERENCES. 31(3) |
| ISSN: | 1476-4431 |
| Popis: | OBJECTIVE To evaluate clinicopathological prognostic indicators associated with survival based on hematology and serum biochemistry profile findings at presentation of dogs with canine parvoviral enteritis (CPE). Secondary objectives were to describe the signalment, history, physical examination findings, and progression of disease while in hospital and correlate them to survival. DESIGN Retrospective study from medical records of dogs diagnosed with CPE between 2001 and 2018. SETTING University teaching hospital. ANIMALS Three hundred twenty-two dogs diagnosed with CPE that received in-hospital treatment. INTERVENTIONS None. MEASUREMENTS AND MAIN RESULTS Of 322 hospitalized dogs, 294 dogs (91%) survived infection with a median hospitalization time of 79 hours. Multivariable analysis showed that glucose (P = 0.04), total magnesium (P = 0.011), and the dichotomized variable of a low HCT (P = 0.033) on presentation were significantly associated with survival. For every 1 mmol/L (18 mg/dL) decrease in glucose concentration, cases had 1.85 lower odds of survival. For every 0.1 mmol/L (0.2 mEq/L) increase in total magnesium concentration, cases had 2.50 lower odds of survival. Cases with a low HCT had 10.69 lower odds of survival. On univariable analyses, non-survivors had a lower median body weight (P = 0.006) and presented more commonly for diarrhea (P = 0.015). At least 1 episode of diarrhea (P = 0.003) and hematochezia or melena (P |
| Databáze: | OpenAIRE |
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