Breast fibromatosis: Making the case for primary vs secondary subtypes
Autor: | Jessica Aoun, Eli Avisar, Jamie Rosenkrantz Spoont, Alicia Vinyard, Swapna Ghanta, Ahkeel Allen, Rachel Berger |
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Rok vydání: | 2019 |
Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Breast Neoplasms Fibroma 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Internal Medicine medicine Adjuvant therapy Humans In patient skin and connective tissue diseases Retrospective Studies Past medical history Surgical approach business.industry Wide local excision Fibromatosis medicine.disease Radiation therapy Fibromatosis Aggressive Oncology 030220 oncology & carcinogenesis Ipsilateral breast Female Surgery Radiology Neoplasm Recurrence Local business |
Zdroj: | The Breast Journal. 26:697-701 |
ISSN: | 1524-4741 1075-122X |
Popis: | Fibromatosis of the breast is a rare condition that can be locally aggressive. The mainstay of treatment remains wide local excision, with varied adjuvant therapy as needed. The authors describe their experience in the treatment of a series of patients and propose the classification of primary and secondary breast fibromatosis. A single-institution retrospective analysis of patients treated for breast fibromatosis from 2003 to 2017 was completed. Demographic data, pertinent past medical history, and treatment modalities were reviewed. Primary breast fibromatosis was defined as arising in the absence of previous surgery or radiation therapy to the ipsilateral breast. Secondary breast fibromatosis was defined as arising in the setting of previous surgery or radiation therapy to the ipsilateral breast. A total of 16 patients were included with the median age 40 (28-64) years. The average size of the lesion was 6.37 cm (range of 1.5-15 cm). Mean follow-up time was 65 months. Surgical excision was completed in 14 patients, with two recurrences. There were no recurrences in patients with surgical margins >1 cm. Two patients were treated nonsurgically. There were seven patients with primary fibromatosis of the breast and nine patients with secondary fibromatosis of the breast. Fibromatosis of the breast is difficult to diagnose prior to surgical excision. We advocate for the multi-disciplinary treatment of this disease process with an aggressive surgical approach to achieve margins >1 cm. |
Databáze: | OpenAIRE |
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