The place of environmental factors in multiple sclerosis: Genes, environment and the interactions thereof in the etiology of multiple sclerosis
| Autor: | D. Sadovnick |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Canada Multiple Sclerosis Databases Factual Environment Bioinformatics Cohort Studies Pathogenesis 03 medical and health sciences Family studies 0302 clinical medicine Risk Factors Humans Medicine Family Genetic Predisposition to Disease 030212 general & internal medicine Child Gene business.industry Siblings Multiple sclerosis fungi Middle Aged medicine.disease Pedigree Neurology Case-Control Studies Etiology Female Gene-Environment Interaction Neurology (clinical) Child Adopted business 030217 neurology & neurosurgery |
| Zdroj: | Revue Neurologique. 175:593-596 |
| ISSN: | 0035-3787 |
| DOI: | 10.1016/j.neurol.2019.08.003 |
| Popis: | The relative roles of genes and environment (not intra-familial environment) and interactions thereof continue to confound better understanding of the pathogenesis of multiple sclerosis (MS) and can also impact recurrence risks for family members as well as genetic family studies. Strong evidence for non-familial environmental factors is suggested by the change in the sex ratio (female:male) of MS patients over the last four decades. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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