Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia

Autor: Amir Kasaeian, Helia Mojtabavi, Mohammad Abdollahi, Amir H. Davarpanah, Leila Aghaghazvini, Bardia Khosravi, Zeynab Rajabi, Amir Reza Radmard, Majid Sorouri, Fatemeh Azizi, Sara Naybandi Atashi, Fatemeh Motamedi, Marjan Khodabakhshi, Ali Reza Sima
Rok vydání: 2021
Předmět:
CT scan
RT-PCR
reverse-transcription polymerase chain reaction
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
qSOFA
quick sequential organ failure assessment
medicine.medical_treatment
CSS
CT severity score
Computed tomography
Disease
030204 cardiovascular system & hematology
Critical Care and Intensive Care Medicine
Logistic regression
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
Article
ICU Admission
03 medical and health sciences
0302 clinical medicine
Internal medicine
otorhinolaryngologic diseases
Medicine
Intubation
Mortality
medicine.diagnostic_test
business.industry
COVID-19
Retrospective cohort study
medicine.disease
Predictive value
Pneumonia
surgical procedures
operative
030228 respiratory system
Cardiology and Cardiovascular Medicine
business
COVID-19
coronavirus disease 19
LOS
length of stay
Zdroj: Heart & Lung
ISSN: 0147-9563
DOI: 10.1016/j.hrtlng.2020.10.005
Popis: Highlights • CT severity score (CSS) could predict ICU admission, intubation, and mortality. • Reticular pattern in lung CT scans, could be protective against adverse outcomes. • CSS was weakly correlated with initial qSOFA score. • CSS could not predict the length of stay in hospital.
Background Chest computed tomography (CT) scan is frequently used in the diagnosis of COVID-19 pneumonia. Objectives This study investigates the predictive value of CT severity score (CSS) for length-of-stay (LOS) in hospital, initial disease severity, ICU admission, intubation, and mortality. Methods In this retrospective study, initial CT scans of consecutively admitted patients with COVID-19 pneumonia were reviewed in a tertiary hospital. The association of CSS with the severity of disease upon admission and the final adverse outcomes was assessed using Pearson's correlation test and logistic regression, respectively. Results Total of 121 patients (60±16 years), including 54 women and 67 men, with positive RT-PCR tests were enrolled. We found a significant but weak correlation between CSS and qSOFA, as a measure of disease severity (r: 0.261, p = 0.003). No significant association was demonstrated between CSS and LOS. Patients with CSS>8 had at least three-fold higher risk of ICU admission, intubation, and mortality. Conclusions CSS in baseline CT scan of patients with COVID-19 pneumonia can predict adverse outcomes and is weakly correlated with initial disease severity.
Databáze: OpenAIRE
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