Chiral spiro phosphoric acid-catalysed enantioselective reaction of ketenes with N–H pyrroles
| Autor: | Li-Feng Chu, Chong-Dao Lu, Yun Yao, Qian-Yi Wang, Teng-Fei Liu |
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| Rok vydání: | 2021 |
| Předmět: |
Chemistry
Metals and Alloys Enantioselective synthesis chemistry.chemical_element General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound Nucleophile Materials Chemistry Ceramics and Composites Organic chemistry Carbon Phosphoric acid |
| Zdroj: | Chemical Communications. 57:11992-11995 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/d1cc05307h |
| Popis: | In the presence of a chiral spiro phosphoric acid catalyst, the asymmetric reaction of disubstituted ketenes with N-H pyrroles occurred to afford enantioenriched C-acylated pyrroles bearing α-stereogenic carbon centres. The described reaction constitutes a rare example of a catalytic asymmetric reaction of ketenes with carbon-based nucleophiles. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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