Glycemic control and outcomes of hospitalization in noncritically ill patients with type 2 diabetes admitted with cardiac problems or infections
| Autor: | Neda Rasouli, Yunjiao Wang, Cecilia C. Low Wang, R. Matthew Hawkins, Stacey A. Seggelke, Boris Draznin, Mark Bridenstine, Joanna Gibbs |
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| Rok vydání: | 2014 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Pediatrics Endocrinology Diabetes and Metabolism Deep vein Type 2 diabetes law.invention Endocrinology law Diabetes mellitus Medicine Humans Intensive care medicine Glycemic Retrospective Studies Type 1 diabetes business.industry Retrospective cohort study General Medicine medicine.disease Intensive care unit Hospitalization Parenteral nutrition medicine.anatomical_structure Diabetes Mellitus Type 1 Diabetes Mellitus Type 2 Hyperglycemia business |
| Zdroj: | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 20(12) |
| ISSN: | 1530-891X |
| Popis: | Although the importance of glycemic control is well established for patients with diabetes hospitalized for surgical problems, it has not been supported by clinical studies for patients with diabetes hospitalized on the medical floors.We conducted a retrospective study of 378 patients with type 2 diabetes admitted for cardiac or infectious disease (ID) diagnosis between September 1, 2011, and August 1, 2012. Exclusion criteria included type 1 diabetes, admission to the intensive care unit (ICU), hospital stay shorter than 3 days, and daily glucocorticoid dose20 mg of methylprednisolone. The primary composite outcome included death during hospitalization, ICU transfer, initiation of enteral or parenteral nutrition, line infection, deep vein thrombosis, pulmonary embolism, rise in plasma creatinine by 1 or2 mg/dL, new infection, an infection lasting for more than 20 days, and readmission within 30 days and between 1 and 10 months after discharge.Patients were stratified by mean blood glucose (BG) level: group 1 had mean BG of180 mg/dL (n = 286; mean BG, 142 ± 23 mg/dL), whereas group 2 had mean BG levels181 mg/dL (n = 92; mean BG, 218 ± 34 mg/dL; P.0001). Group 2 had a 46% higher occurrence of the primary outcome (P.0004). The rate of unfavorable events was greater in cardiac and ID patients with worse glycemic control (group 2).Our data strongly support a positive influence of better glycemic control (average glycemia180 mg/dL or 10 mmol/L) on outcomes of hospitalization in patients with type 2 diabetes. |
| Databáze: | OpenAIRE |
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