Supporting Information from Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells

Autor: Alessandro D. Santin, W. Mark Saltzman, Babak Litkouhi, Peter E. Schwartz, Dan-Arin Silasi, Masoud Azodi, Elena Ratner, Julio Alvarenga, Mitchell Clark, Christopher de Haydu, Gary Altwerger, Luca Zammataro, Federica Predolini, Fan Yang, Elena Bonazzoli, Carlton L. Schwab, Jonathan D. Black, Gulden Menderes, Jiajia Cui, Stefania Bellone, Ken Lin, Salvatore Lopez, Ileana Bortolomai, Erik M. Shapiro, Yang Deng, Emiliano Cocco
Rok vydání: 2023
Popis: Supporting information include 3 tables and 3 figures. Table 1 describes the Patients characteristics from which primary cell lines were established. Table 2 the characteristics of ovarian tumor samples from which RNA was extracted. Table 3 the characterization of particle formulations Supplementary figure 1 shows the DNA release in vitro in culture medium. The Supplementary figure 2 the ovarian tumors' uptake of c-CPE-NP in vivo. The Supplementary figure 3 shows the survival curves of the tumor bearing mice treated with vehicle, c-CPE-NP encapsulating the empty plasmid or the p16 DTA c-CPE-NP.
Databáze: OpenAIRE