Step-economic synthesis of (+)-crocacin C: a concise crotylboronation/[3,3]-sigmatropic rearrangement approach

Autor:	Chris Hamman, Yanzhou Liu, Adele E. Pasqua, James J. Crawford, Frank D. Ferrari, Rodolfo Marquez
Rok vydání:	2012
Předmět:	Antifungal Boron Compounds Antifungal Agents Magnetic Resonance Spectroscopy Molecular Structure medicine.drug_class Chemistry fungi Organic Chemistry food and beverages Total synthesis Stereoisomerism Sigmatropic reaction Alkenes Combinatorial chemistry Amides Yield (chemistry) medicine Crocacin C
Zdroj:	The Journal of organic chemistry. 77(16)
ISSN:	1520-6904
Popis:	The step-economic total synthesis of (+)-crocacin C has been achieved in 20% yield from commercially available starting materials. This approach requires the isolation of only 8 intermediates and can provide a reliable supply of (+)-crocacin C for the development of new antifungal and crop protection agents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ca0120c2910592b398c9c9b3253404 https://pubmed.ncbi.nlm.nih.gov/22804781 Zobrazit plný text záznamu