Does a Gluten-free Diet Improve Metabolic Syndrome Parameters? A Systematic Review
| Autor: | Luciana Gonçalves Orange, Maria Izabel Siqueira de Andrade, Cybelle Rolim Lima, Keila Fernandes Dourado, Thayná Menezes Santos, Marina Moraes Petribu, Priscilla Regia de Andrade Calaça, Silvia Alves Silva |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International Journal of Cardiovascular Sciences, Volume: 35, Issue: 6, Pages: 803-813, Published: 22 APR 2022 International Journal of Cardiovascular Sciences, Issue: ahead, Published: 22 APR 2022 International Journal of Cardiovascular Sciences v.35 n.6 2022 International Journal of Cardiovascular Sciences Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
| Popis: | To review scientific evidence on the effects of a gluten-free diet on body composition and improvement of clinical and biochemical parameters of metabolic syndrome. The Preferred Reporting Items for Systematic Reviews and Meta-Analyzes - PRISMA guidelines were followed. A literature search was performed in the PubMed, ScienceDirect, Trip Database, Bireme and Scielo databases, without language restriction, until March 2021. The terms “gluten-free diet”, “obesity”, “metabolic syndrome”, and “weight loss”, and Boolean operators (AND/OR) were used. The clinical hypothesis was structured according to the acronym PICOT. Randomized clinical trials with adult and elderly humans without a diagnosis of celiac disease, consuming a gluten-free diet, evaluating associations of the effects of this diet on weight loss and metabolic syndrome components were considered eligible. To assess the risk of bias, the RoB2 was used. A total of 3,198 articles were identified and, after the screening and evaluation of pre-defined eligibility criteria, four studies were included in the qualitative analysis. Weight loss was not associated with a gluten-free diet. However, individuals under a gluten-free diet had lower mean waist circumference, fat percentage (-2.3%) and serum triglyceride levels. The impact of a gluten-free diet on metabolic syndrome parameters is still controversial. In individuals without gluten sensitivity or celiac disease, the consumption of a gluten-free diet appears to provide no nutritional benefit. |
| Databáze: | OpenAIRE |
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