Modulation of atrial natriuretic peptide-induced cGMP accumulation by [Arg8]vasopressin in the cultured renal epithelial cell line, LLC-PK1
| Autor: | D. Neuser, Johannes-Peter Stasch, Frank J. Morich |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Pharmacology
Vasopressin medicine.medical_specialty Kidney urogenital system Diuresis Peptide hormone Biology Epithelium In vitro Cell Line Arginine Vasopressin medicine.anatomical_structure Endocrinology Atrial natriuretic peptide Cell culture Internal medicine cardiovascular system medicine Cyclic GMP Atrial Natriuretic Factor hormones hormone substitutes and hormone antagonists Intracellular |
| Zdroj: | European Journal of Pharmacology. 146:341-344 |
| ISSN: | 0014-2999 |
| DOI: | 10.1016/0014-2999(88)90313-5 |
| Popis: | Atrial natriuretic peptide (ANP) III stimulated the formation of intracellular cGMP in renal epithelial cells (LLC-PK1) dose dependently. Incubation of LLC-PK1 cells with [Arg8]vasopressin resulted in an increase in intracellular cAMP levels. The stimulatory effect of ANP III on the cyclic cGMP system was inhibited by coincubation with [Arg8]vasopressin in a dose-dependent manner. |
| Databáze: | OpenAIRE |
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