On using signal magnitude in diffusion magnetic resonance measurements of restricted motion

Autor: Alpay Ozcan
Přispěvatelé: Acibadem University Dspace
Rok vydání: 2019
Předmět:
Diffusion-weighted magnetic resonance imaging
Open problem
Biomedical Engineering
Biophysics
Magnitude (mathematics)
FOS: Physical sciences
Systems and Control (eess.SY)
Electrical Engineering and Systems Science - Systems and Control
Signal
030218 nuclear medicine & medical imaging
Diffusion
Motion
03 medical and health sciences
symbols.namesake
0302 clinical medicine
Magnetic resonance imaging
FOS: Electrical engineering
electronic engineering
information engineering

Humans
Computer Simulation
Radiology
Nuclear Medicine and imaging

Diffusion (business)
Physics
Fourier Analysis
Basis (linear algebra)
Reproducibility of Results
Signal Processing
Computer-Assisted

Models
Theoretical

Physics - Medical Physics
Hermitian matrix
Symmetry (physics)
Computational physics
Diffusion Magnetic Resonance Imaging
Fourier transform
symbols
Medical Physics (physics.med-ph)
030217 neurology & neurosurgery
Popis: Tissue microstructure has significance as a biomarker, however its accurate inference with diffusion magnetic resonance (MR) is still an open problem. With few exceptions, diffusion weighted (DW) MR models either process diffusion MR data using signal magnitude, whereby microstructural information is forcefully confined to symmetry due to Fourier transform properties, or directly use symmetric basis expansions. Herein, information loss from magnitude utilization is demonstrated by numerically simulating particles undergoing diffusion near a fully reflective infinite wall and an orthogonal corner. Simulation results show that the loss of the Hermitian property when using signal magnitude impedes DW--MR from accurately inferring microstructural information in both of the geometries.
Databáze: OpenAIRE