Quality of Life in Octogenarians After Lung Resection Compared to Younger Patients
| Autor: | Andrea Bille, Igor Saftic, John Pilling, Juliet King, Thomas Tsitsias, Nicole Asemota |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Adult
Male 0301 basic medicine Pulmonary and Respiratory Medicine Cancer Research medicine.medical_specialty Lung Neoplasms Octogenarians Health Behavior 03 medical and health sciences 0302 clinical medicine Age groups Quality of life Carcinoma Non-Small-Cell Lung Surveys and Questionnaires medicine Humans Postoperative outcome In patient Postoperative Period Lung cancer Aged Aged 80 and over business.industry social sciences Middle Aged medicine.disease humanities Surgery 030104 developmental biology Socioeconomic Factors Oncology 030220 oncology & carcinogenesis Quality of Life Female Lung resection business Follow-Up Studies |
| Zdroj: | Clinical Lung Cancer. 23:e118-e130 |
| ISSN: | 1525-7304 |
| DOI: | 10.1016/j.cllc.2021.05.008 |
| Popis: | To evaluate postoperative outcome and quality of life (QOL), comparing patients80 years old to patients ≥ 80.EORTC questionnaires, QLQ-C30 and QLQ-LC13 was used to assess QOL, in patients after surgery. Results were evaluated according to 3 age groups:70, 70 to 79, and ≥80.106 patients were enrolled with 33 (70), 25 (70-79), and 48 (≥80) patients per group. The median age was 74 years. 79% of patients had minimally invasive procedures, including 91% of those ≥80. Fifteen patients underwent wedge resections. Complication rates (18%, 32%, and 29%, P = .4) and median length of stay (4, 6, and 5 days, P = .2) were similar in all age groups, with no hospital mortality. One hundred one patients completed the questionnaires. Global QOL was highest among octogenarians. Overall functional and role QOL was higher among octogenarians than 70- to 79-year-olds, with emotional QOL higher than those70 (P.05). Social QOL in octogenarians was marginally lower than younger patients. Lung-specific symptom scores were at least 1.5 times lower than those80 (P = .052). Patients aged 70 to 79 had the worst symptomatic and emotional effect on QOL. Surgical access and preoperative performance status did not affect final QOL across all age groups (P = .9 and P = .065). Among anatomical lung resections, QOL was higher in octogenarians than those 70 to 79 in all domains, and similar or higher than those70 in most domains.Quality of life among octogenarians after surgery remains similar to younger patients even after anatomical lung resection. Surgery in octogenarians is safe, with minimal impact on postoperative QOL. |
| Databáze: | OpenAIRE |
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