Evaluation of Multi-Scale Multiple Instance Learning to Improve Thyroid Cancer Classification
Autor: | Maximilian E. Tschuchnig, Philipp Grubmuller, Lea M. Stangassinger, Christina Kreutzer, Sebastien Couillard-Despres, Gertie J. Oostingh, Anton Hittmair, Michael Gadermayr |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: |
FOS: Computer and information sciences
Computer Science - Machine Learning Computer Vision and Pattern Recognition (cs.CV) Image and Video Processing (eess.IV) FOS: Electrical engineering electronic engineering information engineering Computer Science - Computer Vision and Pattern Recognition Electrical Engineering and Systems Science - Image and Video Processing Machine Learning (cs.LG) |
Popis: | Thyroid cancer is currently the fifth most common malignancy diagnosed in women. Since differentiation of cancer sub-types is important for treatment and current, manual methods are time consuming and subjective, automatic computer-aided differentiation of cancer types is crucial. Manual differentiation of thyroid cancer is based on tissue sections, analysed by pathologists using histological features. Due to the enormous size of gigapixel whole slide images, holistic classification using deep learning methods is not feasible. Patch based multiple instance learning approaches, combined with aggregations such as bag-of-words, is a common approach. This work's contribution is to extend a patch based state-of-the-art method by generating and combining feature vectors of three different patch resolutions and analysing three distinct ways of combining them. The results showed improvements in one of the three multi-scale approaches, while the others led to decreased scores. This provides motivation for analysis and discussion of the individual approaches. Accepted and presented at IPTA 2022 |
Databáze: | OpenAIRE |
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