Aggressive thoracotomy for pulmonary metastatic osteogenic sarcoma in children and young adolescents
| Autor: | Gerald S. Gilchrist, Mao-Tang Han, Douglas J. Pritchard, W. Spencer Payne, Robert L. Telander, Peter C. Pairolero, Franklin H. Sim |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male medicine.medical_specialty Lung Neoplasms Adolescent medicine.medical_treatment Bone Neoplasms Young adolescents Actuarial Analysis Methods medicine Humans Pulmonary metastasis Thoracotomy Metastatic Osteogenic Sarcoma Young adult Child Lung Osteosarcoma Surgical approach business.industry General Medicine medicine.disease Surgery Child Preschool Pediatrics Perinatology and Child Health Female Sarcoma business Median survival |
| Zdroj: | Journal of Pediatric Surgery. 16:928-933 |
| ISSN: | 0022-3468 |
| Popis: | During a 6-yr period, 57 children and young adults less than 21 yr of age underwent 111 thoracotomies for pulmonary metastatic osteogenic sarcoma. Follow-up after the initial thoracotomy averaged 36.8 no and ranged from 1 to 78 mo. Twenty-eight patients (49%) underwent more than one thoracotomy--the number of multiple thoracotomies averaged 2.9 and ranged from two to eight. Twenty-six of the 57 patients are currently alive, and 25 of these are free of disease. Median survival was 36 mo. Actuarial survival curves demonstrated a 5-yr survival of approximately 40%. Seventy-one percent of patients who had a tumor-free interval of greater than 1 yr are currently alive, compared with 39% of patients who had a tumor-free interval of less than 1 yr. Patients with disease confined to one lobe at the initial thoracotomy had a better survival (64%) than patients with diffuse or bilateral disease (41%). An aggressive surgical approach toward osteogenic sarcoma with pulmonary metastasis thus appears to be justified. |
| Databáze: | OpenAIRE |
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