SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2
| Autor: | Alexander M. Arutyunyan, Bakhtiyar I. Verdiev, Gleb Zhdanov, Maria A. Nikiforova, Liubov I. Popova, Artem P. Tkachuk, Oganes Ambartsumyan, Dmitry Gribanyov, Anna A. Iliukhina, Artem G. Alatyrev, Alexandra S. Gambaryan, Elena V. Rudakova, Inna V. Dolzhikova, Nadezhda P. Kuznetsova, V. A. Kukushkin, Elena Zavyalova, Anna V. Ignatieva, Vladimir A. Gushchin, Elena Burtseva |
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| Rok vydání: | 2021 |
| Předmět: |
respiratory viral infections
Coronavirus disease 2019 (COVID-19) General Chemical Engineering Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Aptamer Nanotechnology 02 engineering and technology DNA Aptamers 010402 general chemistry 01 natural sciences Article General Materials Science optical sensor QD1-999 SARS-CoV-2 SERS Chemistry COVID-19 silver colloids aptamer 021001 nanoscience & nanotechnology Quantitative determination 0104 chemical sciences Virus detection 0210 nano-technology Biosensor |
| Zdroj: | Nanomaterials Volume 11 Issue 6 Nanomaterials, Vol 11, Iss 1394, p 1394 (2021) |
| ISSN: | 2079-4991 |
| DOI: | 10.3390/nano11061394 |
| Popis: | During the COVID-19 pandemic, the development of sensitive and rapid techniques for detection of viruses have become vital. Surface-enhanced Raman scattering (SERS) is an appropriate tool for new techniques due to its high sensitivity. SERS materials modified with short-structured oligonucleotides (DNA aptamers) provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection are either inapplicable for quantitative determination or have sophisticated and expensive construction and implementation. In this paper, we provide a SERS-aptasensor based on colloidal solutions which combines rapidity and specificity in quantitative determination of SARS-CoV-2 virus, discriminating it from the other respiratory viruses. |
| Databáze: | OpenAIRE |
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