Radiofrequency thermotherapy for malignant liver tumors
| Autor: | Yasushi Nagata, Masaji Takahashi, Shiken Jo, Hiroo Imura, Masahiro Hiraoka, Shin-ichirou Masunaga, Masahiro Fukuda, Yasumasa Nishimura, Keizo Akuta, Mitsuyuki Abe |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Hyperthermia Cancer Research Pathology medicine.medical_specialty Carcinoma Hepatocellular Liver tumor Radiofrequency thermotherapy Radio Waves medicine.medical_treatment Gastroenterology Tumor temperature Radiotherapy High-Energy Adenoma Bile Duct Internal medicine medicine Humans Diffuse type Embolization neoplasms Aged Aged 80 and over business.industry Liver Neoplasms Temperature Complete remission Hyperthermia Induced Middle Aged medicine.disease University hospital Combined Modality Therapy Embolization Therapeutic digestive system diseases Oncology Doxorubicin Colonic Neoplasms Female business |
| Zdroj: | Cancer. 65:1730-1736 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(19900415)65:8<1730::aid-cncr2820650812>3.0.co;2-d |
| Popis: | Inoperable malignant liver tumors have been treated by radiofrequency hyperthermia at Kyoto University Hospital since 1983. In this study, clinical hyperthermia for malignant liver tumor was evaluated for 67 tumors in which we could measure intratumor temperatures. Of the 67 tumors, 41 were hepatocellular carcinomas (HCC), six cholangiocarcinomas, and 20 metastatic tumors. Cholangiocarcinoma and metastatic tumors were more susceptible to this treatment than HCC. Of the three types of HCC, higher intratumor temperatures were achieved in the diffuse type than in the nodular or massive types. The minimum tumor temperature of HCC stayed below 40 degrees C in 46% of cases, especially in larger tumors. The local response rates (complete remission plus partial remission/all) were 28% and 11% for HCC and non-HCC, respectively, for thermochemotherapy; 86% and 33%, for thermoradiotherapy; and 33% and 89%, for thermotherapy with embolization. No apparent relationship was observed between the intratumor temperatures and local response rate. |
| Databáze: | OpenAIRE |
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