Involvement of a Phage-Encoded Wzy Protein in the Polymerization of K127 Units To Form the Capsular Polysaccharide of Acinetobacter baumannii Isolate 36-1454

Autor: Nikolay P. Arbatsky, Anastasiya A. Kasimova, Alexander S. Shashkov, Mikhail M. Shneider, Anastasiya V. Popova, Dmitry A. Shagin, Andrey A. Shelenkov, Yuliya V. Mikhailova, Yurii G. Yanushevich, Ruth M. Hall, Yuriy A. Knirel, Johanna J. Kenyon
Rok vydání: 2022
Předmět:
Zdroj: Microbiology Spectrum. 10
ISSN: 2165-0497
Popis: Bacteriophage therapy is an attractive innovative treatment for infections caused by extensively drug resistant Acinetobacter baumannii , for which there are few effective antibiotic treatments remaining. Capsular polysaccharide (CPS) is a primary receptor for many lytic bacteriophages, and thus knowledge of the chemical structures of CPS produced by the species will underpin the identification of suitable phages for therapeutic cocktails.
Databáze: OpenAIRE