Zinc(II) complexes derived from imidazo[1,2-a]pyridin-2-ylacetic acid (HIP-2-ac): [Zn(IP-2-ac)2(H2O)] and unexpectedly, [Zn3(IP-2-ac)6(H2O)]·11H2O

Autor: Bogumiła Szponar, Piotr Drożdżewski, Agnieszka Dylong, Katarzyna Ślepokura, Waldemar Goldeman, Ewa Matczak-Jon, Michał Sowa
Rok vydání: 2015
Předmět:
Zdroj: Journal of Coordination Chemistry. 68:2208-2224
ISSN: 1029-0389
0095-8972
Popis: Two zinc(II) complexes based on imidazo[1,2-a]pyridin-2-ylacetate (IP-2-ac), [Zn(IP-2-ac)2(H2O)] (1) and [Zn3(IP-2-ac)6(H2O)]·11H2O (2), were synthesized and characterized by single-crystal X-ray diffraction. In both 1 and 2, zinc(II) ions are five-coordinate with N2O3 donor set, best described as a distorted trigonal-bipyramidal geometry. In 1, two IP-2-ac ligands chelate zinc(II) through a N,O donor set, whereas in 2, both bidentate and μ-bridging binding modes of IP-2-ac are observed. The crystal of 1 comprises discrete Zn(IP-2-ac)2(H2O) coordination entities combined into layers by hydrogen bonds. Inter-layer stabilization of the 3-D crystal lattice is provided by weak C–H⋯O contacts and π⋯π interactions. The structure of 2 consists of discrete trinuclear Zn3(IP-2-ac)6(H2O) coordination entities joined into crystal lattice by multiple water molecules.Compound 1 was characterized by FTIR and FT-Raman spectroscopy, and in terms of thermal stability. Furthermore, its antibacterial activity was tested against selected gram-positive, gram-negative bacteria, and Candida albicans yeast and compared with activity of previously reported [M(IP-2-ac)2(H2O)2]·2H2O (M = Co, Ni, Mn, Cd) complexes.
Databáze: OpenAIRE
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