Myocardial perfusion at rest in uncomplicated type 2 diabetes patients without coronary artery disease evaluated by 320-multidetector computed tomography: A pilot study
| Autor: | Xueqing Guan, Jin Fang, Shuihua Zhang, Dabiao Deng, Xiangyi Cai, Quan Zhou, Honglin Li |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Observational Study Pilot Projects Type 2 diabetes 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences Coronary circulation Myocardial perfusion imaging 0302 clinical medicine Internal medicine Coronary Circulation Multidetector Computed Tomography Medicine Humans Prospective Studies Prospective cohort study medicine.diagnostic_test business.industry Myocardial Perfusion Imaging computed tomography General Medicine Middle Aged medicine.disease medicine.anatomical_structure transmural perfusion ratio Diabetes Mellitus Type 2 Ventricle Case-Control Studies diabetes mellitus Cardiology Female business Perfusion Artery Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | Using computed tomography myocardial perfusion imaging (CTP) to investigate resting myocardial perfusion alterations in uncomplicated type 2 diabetes mellitus (T2DM) patients without obstructive coronary artery disease (CAD). A total of 34 participants with 544 myocardial segments were included prospectively: 17 uncomplicated T2DM patients with no significant coronary artery stenosis on coronary computed tomography angiography and 17 healthy controls. Myocardial perfusion was evaluated by transmural perfusion ratio (TPR). Parameters of cardiac structure and function were measured for cardiac comprehensive assessment. Analyses included descriptive statistics and group comparisons. TPR of segments 5, 7, 9, 10 to 14 were significantly reduced in T2DM group compared with controls (P |
| Databáze: | OpenAIRE |
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