Botryoid Rhabdomyosarcoma of the Conjunctiva in a Young Boy
| Autor: | R Joel Welch, Justin D Pennington, Jerry A. Shields, Sara E. Lally, Ralph C. Eagle, Carol L. Shields |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Pathology medicine.medical_specialty tumor Conjunctiva conjunctiva Biopsy medicine.medical_treatment MEDLINE Conjunctival Neoplasms Case Report Favorable prognosis 03 medical and health sciences 0302 clinical medicine medicine Humans Rhabdomyosarcoma Letters to Editor business.industry Systemic chemotherapy Fornix Botryoid General Medicine medicine.disease Dermatology eye diseases Radiation therapy Ophthalmology papilloma medicine.anatomical_structure Child Preschool 030220 oncology & carcinogenesis 030221 ophthalmology & optometry Immunohistochemistry Papilloma rhabdomyosarcoma business |
| Zdroj: | Middle East African Journal of Ophthalmology |
| ISSN: | 0975-1599 0974-9233 |
| Popis: | Primary conjunctival rhabdomyosarcoma (RMS) is a rare entity that can present with or without papillomatous features. A 5-year-old Asian boy was referred for a rapidly growing conjunctival tumor in the superior fornix of the left eye. Surgical excision yielded a 28 mm multilobulated papillomatous specimen that exhibited histopathologic and immunohistochemical features consistent with embryonal (botryoid) RMS. Molecular analysis revealed the absence of the PAX3/FOXO1 fusion gene, indicating favorable prognosis. After surgery, he was promptly treated with systemic chemotherapy and proton beam radiotherapy. |
| Databáze: | OpenAIRE |
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