Fine-structure map of the histidine transport genes in Salmonella typhimurium

Autor: H Taber, K D Noel, E N Spudich, J Afong, K Nikaido, Giovanna Ferro-Luzzi Ames
Rok vydání: 1977
Předmět:
Zdroj: Journal of Bacteriology. 129:1289-1297
ISSN: 1098-5530
0021-9193
DOI: 10.1128/jb.129.3.1289-1297.1977
Popis: Afine-structure genetic map of the histidine transport region of the Salmonella typhimurium chromosome was constructed. Twenty-five deletion mutants were isolated and used for dividing the hisJ and hisP genes into 8 and 13 regions respectively. A total of 308 mutations, spontaneous and mutagen induced, have been placed in these regions by deletion mapping. The histidine transport operon is presumed to be constituted of genes dhuA, hisJ, and hisP, and the regulation of the hosP and hisJ genes by dhuA is discussed. The orientation of this operon relative to purF has been established by three-point crosses as being: purF duhA hisJ hisP.
Databáze: OpenAIRE