NH4OAc Promoted Cyclocondensation of 3-(o-Allylphenyl)pentane-1,5-diones: Synthesis of Tetracyclic Benzofused 1-Azahomoisotwistanes
| Autor: | Hang-Yi Tai, Meng-Yang Chang, Ming-Hao Wu |
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| Rok vydání: | 2012 |
| Předmět: |
Molecular Structure
Aryl Organic Chemistry Molecular Conformation Acetates Ketones Crystallography X-Ray Heterocyclic Compounds 4 or More Rings Biochemistry Catalysis Pentane chemistry.chemical_compound chemistry Pentanes Yield (chemistry) Organic chemistry Physical and Theoretical Chemistry Azabicyclo Compounds |
| Zdroj: | Organic Letters. 14:3936-3939 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/ol301693s |
| Popis: | A facile two-step synthetic route for preparing the novel tetracyclic skeleton of benzofused 2,6-diaryl-1-azahomoisotwistanes 2 had been developed. The route was carried out by a one-pot tandem cross-coupling reaction of o-allylbenzaldehydes 1 with aryl methyl ketones 3, and NH(4)OAc mediated the cascade cyclocondensation reaction of the resulting 1,5-diketones 4 with the 3-o-allylphenyl group in good yield in two steps. |
| Databáze: | OpenAIRE |
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