Cardiac Troponin T in Neonates after Acute and Long-Term Tocolysis
| Autor: | Milan Košt’ál, Zdeněk Kokštein, Vladimir Palicka, Michaela Adamcova, Jaroslava Vávrová, Miloslava Podholová |
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| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_treatment Tocolysis Electrocardiography Troponin T Troponin complex Pregnancy Blood plasma Humans Medicine Creatine Kinase Chemotherapy biology business.industry Myocardium Infant Newborn Adrenergic beta-Agonists Fetal Blood Troponin Isoenzymes Tocolytic Agents In utero Tocolytic Anesthesia Cord blood Pediatrics Perinatology and Child Health biology.protein Female Creatine kinase Cardiomyopathies business Developmental Biology |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1661-7819 1661-7800 |
| DOI: | 10.1159/000014281 |
| Popis: | The present study was designed to determine the levels of cardiac troponin T (cTnT) in cord blood of neonates exposed in utero to tocolytic therapy by β-sympathomimetics. cTnT in 40 neonates after acute tocolysis (0.24 ± 0.05 μg/l) was significantly higher (p < 0.05) in comparison with the control group (0.05 ± 0.01 μg/l). The maximal values were reached in about the 3rd day of therapy (0.39 ± 0.11 μg/l). cTnT in 30 neonates after long-term tocolysis was 0.12 ± 0.03 μg/l. No correlation was found between cTnT and CK and its isoenzyme CK-MB or ECG. CK, unlike cTnT, significantly correlated with gestational age (r = 0.57, p < 0.05) and birth weight (r = 0.55, p < 0.05). It is possible to conclude that acute tocolytic therapy by β-sympathomimetics increases the cTnT levels in cord blood and cardiac troponin T is more useful for the laboratory diagnosis of neonatal myocardial injury than CK-MB. |
| Databáze: | OpenAIRE |
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