Effect of Helicobacter pylori eradication in the glycemia of children with type 1 diabetes: a preliminary study

Autor:	RODOLFO E. BÉGUÉ, RICARDO GÓMEZ, TERRY COMPTON, ALFONSO VARGAS
Rok vydání:	2002
Předmět:	Glycated Hemoglobin Male Time Factors Adolescent Helicobacter pylori General Medicine Anti-Bacterial Agents Helicobacter Infections Diabetes Mellitus Type 1 Clarithromycin Metronidazole Humans Female Child Follow-Up Studies
Zdroj:	Southern medical journal. 95(8)
ISSN:	0038-4348
Popis:	We previously reported that children with diabetes and Helicobacter pylori infection had higher levels of glycated hemoglobin (HbA1c) than uninfected peers. We sought to determine whether eradication of the infection could decrease their HbA1c level.Eight children with type 1 diabetes and H. pylori infection (cases) were treated to eradicate the infection. Cases were matched (2:1) with uninfected diabetic children (controls), and their HbA1c levels were monitored.As previously described, cases started with higher HbA1c values than controls. More than 2 years after treatment, cases showed a decreasing trend and controls an increasing trend in HbA1c values. At the end of the study, cases and controls had comparable HbA1c values.These data suggest that eradication of H. pylori infection in patients with type 1 diabetes might be associated with better control of glycemia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85835f54c356f3ddc10e08a4b93bf6e5 https://pubmed.ncbi.nlm.nih.gov/12190218 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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