Group Means and Inter-Individual Analysis in Post-exercise Hypotension: Effects of Citrulline Malate Oral Supplementation
| Autor: | Brito, Leandro C. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
lcsh:Diseases of the circulatory (Cardiovascular) system Time Factors Doenças Cardiovasculares Vasodilator Agents Exercício Malates Blood Pressure Citruline Citrulina chemistry.chemical_compound Reference Values Citrulline Medicine Amino Acids Aged 80 and over Anthropometry Middle Aged Treatment Outcome Cardiovascular Diseases Anesthesia Hypertension Female Original Article Post-Exercise Hypotension Short Editorial Cardiology and Cardiovascular Medicine Adult Citrulline malate Arginine Nitric Oxide Statistics Nonparametric Blood Pressure Monitoring Ambulatory Individual analysis Double-Blind Method Humans Exercise Aged Analysis of Variance business.industry Placebo Effect Blood pressure chemistry lcsh:RC666-701 Dietary Supplements Mortalidade & Morbidade Exercise Test Mortality & Morbidity Hipotensão Pós-Exercício Pressão Arterial business Hipertensão |
| Zdroj: | Arquivos Brasileiros de Cardiologia, Volume: 113, Issue: 2, Pages: 229-230, Published: 02 SEP 2019 Arquivos Brasileiros de Cardiologia Arquivos Brasileiros de Cardiologia, Vol 113, Iss 2, Pp 229-230 |
| Popis: | Background Studies have persuasively demonstrated that citrulline has a key role in the arginine-nitric oxide system, increasing nitric oxide bioavailability, an important mediator of peripheral vasodilation. Objective To analyze the inter-individual post-exercise hypotension responsiveness following acute citrulline supplementation in hypertensives. Methods Forty hypertensives were randomly assigned to one of the four experimental groups (control-placebo, control-citrulline, exercise-placebo, and exercise-citrulline). They ingested placebo or citrulline malate [CM] (6 grams). During the exercise session, individuals performed 40 minutes of walking/running on a treadmill at 60-70% of HR reserve. For the control session, the individuals remained seated at rest for 40 minutes. Office blood pressure (BP) was taken every 10 minutes until completing 60 minutes after the experimental session. The ambulatory BP device was programmed to take the readings every 20 minutes (awake time) and every 30 minutes (sleep time) over the course of 24 hours of monitoring. Statistical significance was defined as p < 0.05. Results Unlike the other experimental groups, there were no “non-responders” in the exercise/citrulline (EC) for “awake” (systolic and diastolic BP) and “24 hours” (diastolic BP). The effect sizes were more consistent in the EC for systolic and diastolic ambulatorial BP response. The effects were “large” (> 0.8) for “awake”, “asleep”, and “24 hours” only in the EC for diastolic BP. Conclusion CM supplementation can increase the post-exercise hypotensive effects in hypertensives. In addition, the prevalence of non-responders is lower when associated with aerobic exercise and CM supplementation. |
| Databáze: | OpenAIRE |
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