Role of Human Papillomavirus DNA Load in Predicting the Long-term Risk of Cervical Cancer: A 15-Year Prospective Cohort Study in China

Autor: Xuelian Zhao, Shuang Zhao, Xun Zhang, Kevin Zhao, Shang-Ying Hu, Qin-Jing Pan, Fang-Hui Zhao, Qian Zhang
Rok vydání: 2018
Předmět:
Zdroj: The Journal of Infectious Diseases. 219:215-222
ISSN: 1537-6613
0022-1899
Popis: BACKGROUND Biomarkers highly predictive of cervical cancer are urgently needed for triaging human papillomavirus (HPV)-positive women. METHODS A total of 1997 women aged 35-45 years in Shanxi, China, were recruited in 1999, and follow-up visits were conducted in 2005, 2010, and 2014. HPV load was measured by the Hybrid Capture 2 assay. Findings were determined by relative light units/cutoff (RLU/CO) and categorized into 4 groups: negative (
Databáze: OpenAIRE