Comparing newborn outcomes after prenatal exposure to individual antidepressants: A retrospective cohort study
| Autor: | Claire Marks, Evgennia Teal, Sara K. Quinney, Rebecca M. Silvola, David M. Haas |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Population Venlafaxine Citalopram Duloxetine Hydrochloride Article chemistry.chemical_compound Escitalopram Pregnancy Fluoxetine Sertraline Internal medicine mental disorders medicine Humans Duloxetine Pharmacology (medical) education Bupropion Retrospective Studies education.field_of_study business.industry Infant Newborn Venlafaxine Hydrochloride Retrospective cohort study Odds ratio Antidepressive Agents Treatment Outcome chemistry Prenatal Exposure Delayed Effects Female business medicine.drug |
| Zdroj: | Pharmacotherapy |
| ISSN: | 1875-9114 0277-0008 |
| Popis: | OBJECTIVE: To compare associations between individual antidepressants and newborn outcomes. DESIGN: Retrospective cohort study SETTING: Deliveries in a large, US medical system. POPULATION: Women who received at least one antidepressant prescription 3 months prior to conception through delivery. METHODS: Eligible women had maternal characteristics and newborn outcomes extracted from medical record data. Exposure was defined by the timing of the prescription during pregnancy. MAIN OUTCOME MEASURES: Newborn outcomes (any adaptation syndrome, neonatal intensive care unit (NICU) admission) were analyzed for each antidepressant and compared using standard statistics and multivariable regression compared to exposure to bupropion. Odds of outcomes based on timing of exposure were also explored. RESULTS: A total of 3,694 women were analyzed. Rates of any adaptation syndrome (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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