Yb(OTf)3 catalyzed new cascade reaction: a facile assembly of fused quinazolinones
| Autor: | Manojit Pal, C. Malla Reddy, Ahamed A. Jafar, K. Siva Kumar, M. Appi Reddy, S. Pal, P. Mahesh Kumar, K. Shiva Kumar, Md. Ferozuddin, D. Rambabu, Gamidi Rama Krishna, M. Sreenivasulu |
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| Rok vydání: | 2011 |
| Předmět: |
Mesylates
Stereochemistry Tumor Necrosis Factor-alpha Metals and Alloys General Chemistry Ring (chemistry) Small molecule Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound chemistry Cascade reaction Materials Chemistry Ceramics and Composites Organometallic Compounds Moiety Isoquinoline Structural motif Quinazolinones |
| Zdroj: | Chemical communications (Cambridge, England). 47(37) |
| ISSN: | 1364-548X |
| Popis: | A one-pot Yb(III)-mediated cascade reaction has been developed leading to small molecules based on a novel structural motif, i.e. quinazolin-4-one moiety fused with an isoquinoline ring, for potential inhibition of TNF-α. |
| Databáze: | OpenAIRE |
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