The natural history of cardiac rhabdomyoma with and without tuberous sclerosis
| Autor: | P. A. Pellegrino, G Svaluto-Moreolo, André Vliers, Giuliano Bosi, J. P. Lintermans |
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| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Remission Spontaneous Spontaneous remission Rhabdomyoma Heart Neoplasms Neoplasms Multiple Primary Tuberous sclerosis Tuberous Sclerosis medicine Humans Child Retrospective Studies High prevalence business.industry Cardiac rhabdomyoma Infant Newborn Infant Arrhythmias Cardiac Retrospective cohort study General Medicine medicine.disease Surgery Natural history El Niño Child Preschool Pediatrics Perinatology and Child Health cardiovascular system Female business Follow-Up Studies |
| Zdroj: | Acta Paediatrica. 85:928-931 |
| ISSN: | 1651-2227 0803-5253 |
| DOI: | 10.1111/j.1651-2227.1996.tb14188.x |
| Popis: | The aim of the present study is to contribute to the knowledge of the natural history of cardiac rhabdomyoma in children with and without tuberous sclerosis. In a retrospective study, 33 children with cardiac rhabdomyoma were collected from three pediatric cardiology centres. In 30/33 patients tuberous sclerosis was associated. High prevalence of cardiac rhabdomyoma was found in infancy, with 21/23 detected before the age of 1 year, and 11/33 before 1 month of age. Cardiac manifestations were present in 19 patients: cardiac rhythm disturbances were detected in 13; in 6/33 a Wolff-Parkinson-White syndrome was documented, of which 4 presented paroxysmal arrhythmias. Obstructive or regurgitative phenomena were present in 5; and in 2 patients surgical removal proved necessary. With the exception of one tumoural mass in the right atrium, all 77 tumours were located somewhere in the ventricles, including at atrio-ventricular valve level. Because of spontaneous regression of most of the tumoural masses, treatment should at first be symptomatic, while surgical removal is required only in life-threatening conditions, as documented in 2 of our 33 patients. |
| Databáze: | OpenAIRE |
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