Effect of Lactococcus lactis subsp. cremoris YRC3780 on birch pollinosis: a randomized, double-blind, placebo-controlled clinical trial
| Autor: | Jun Nishihira, Naoya Katano, Kenji Uchida, Hidemasa Motoshima, Satoshi Hachimura, Aiko Tanaka |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Allergy medicine.medical_specialty Medicine (miscellaneous) Placebo Placebo group Double blind 03 medical and health sciences 0302 clinical medicine Lactococcus lactis subsp. cremoris Internal medicine Dose group Medicine TX341-641 Thymus and activation-regulated chemokine (TARC) Nutrition and Dietetics Medication score biology business.industry Nutrition. Foods and food supply Lactococcus lactis subsp cremoris Lactococcus lactis biology.organism_classification medicine.disease HOKKAIDO Clinical trial 030104 developmental biology 030228 respiratory system Birch pollinosis business Food Science |
| Zdroj: | Journal of Functional Foods, Vol 43, Iss, Pp 173-179 (2018) |
| ISSN: | 1756-4646 |
| Popis: | In a randomized, double-blind, placebo-controlled trial, 114 patients with birch pollinosis received Lactococcus lactis subsp. cremoris YRC3780 (YRC3780) powder (n = 28, 29, 28, in each dose group) or a placebo (1 g starch powder, n = 29) daily for 12 weeks during the 2016 pollen season. Patients self-recorded their symptom and medication scores daily, and blood samples were evaluated every 4 weeks throughout the treatment observation periods. Symptom and medication scores during the intake period were grouped into 6 consecutive periods of 2 weeks each, and average values were compared between periods. In the YRC3780-treated groups, medication scores were significantly lower than scores in the placebo group during intake periods 3 (P |
| Databáze: | OpenAIRE |
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