Effect of Early and Intensive Rehabilitation after Ischemic Stroke on Functional Recovery of the Lower Limbs: A Pilot, Randomized Trial
| Autor: | Zhe-Wei Wang, Xiaoli Chen, Guo-Qian Chen, Wen-Xiu Wu, Dong-rui He, Cheng-Ye Zhou, Hai-Min Jin |
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| Rok vydání: | 2020 |
| Předmět: |
Male
China medicine.medical_specialty Time Factors medicine.medical_treatment Psychological intervention Pilot Projects Walking Neurological disorder Motor Activity Brain Ischemia Time-to-Treatment law.invention Disability Evaluation 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law medicine Humans Prospective Studies Postural Balance Stroke Aged Rehabilitation business.industry Stroke Rehabilitation Motor control Recovery of Function Middle Aged medicine.disease Functional recovery Bicycling Exercise Therapy Treatment Outcome Lower Extremity Berg Balance Scale Physical therapy Female Surgery Neurology (clinical) Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Stroke and Cerebrovascular Diseases. 29:104649 |
| ISSN: | 1052-3057 |
| DOI: | 10.1016/j.jstrokecerebrovasdis.2020.104649 |
| Popis: | We aimed to develop an early and intense lower extremity training technique using a recumbent cycle ergometer system in patients with acute ischemic stroke.This was a pilot, prospective, randomized, controlled study with 2 parallel groups followed for 3 months with blinded assessment of outcomes. Thirty-one eligible patients were randomized to experimental and control groups. To strengthen the motion of the lower extremities within 48 hours after stroke, the control and experimental groups received conventional treatment and additional interventions under a therapist's guidance combined with conventional treatment, respectively. The primary outcome measure was the change in lower extremity motor control from admission to 4 weeks, assessed by the Fugl-Meyer Assessment. Secondary outcomes were the number of days to walking 50 m and the change in the Berg Balance Scale score and Barthel index. The modified Rankin Score was used to assess the overall function and prognosis at 3 months.Fugl-Meyer Assessment and Berg Balance Scale scores and Barthel index increased over time in the experimental group, as did the Berg Balance Scale score and Barthel index in the control group (P.001). However, Fugl-Meyer Assessment scores in the control group were similar over time (F = 2.303, P = 1.119). Fugl-Meyer Assessment scores in the experimental group were higher than those in the control group after 2 and 4 weeks (P = .084 and .037, respectively). Compared with the control group at 2 weeks or at discharge, the percentage of patients who returned to unassisted walking in the experimental group showed an increasing trend (56.3% versus 26.67%, P = .095), but there was no significant difference between the 2 groups after 3 months (P = .598). The modified Rankin Score at 3 months showed no significant difference between the 2 groups (P.05).Our early and intense lower extremity training technique involving a leg cycle ergometer system contributes to the recovery of lower extremity function in patients with acute ischemic stroke. This finding will provide a basis for future investigations on the applicability of the intervention in early lower extremity and walking rehabilitation among individuals with neurological disorder. |
| Databáze: | OpenAIRE |
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