Emerging concepts of bile reflux in the constellation of gastroesophageal reflux disease
| Autor: | Hubert J. Stein, Werner K. H. Kauer |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Esophageal pH Monitoring Esophageal Neoplasms Disease Adenocarcinoma digestive system Gastroenterology Pathogenesis Bile reflux Bile Acids and Salts Barrett Esophagus Dogs Internal medicine Electric Impedance Medicine Animals Humans Esophagus Esophagitis Peptic Gastric Juice medicine.diagnostic_test business.industry digestive oral and skin physiology Bile Reflux Reflux Bilirubin medicine.disease Immunohistochemistry digestive system diseases Rats medicine.anatomical_structure GERD Gastroesophageal Reflux Surgery Rabbits business Esophageal pH monitoring Esophagitis |
| Zdroj: | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 14 |
| ISSN: | 1873-4626 |
| Popis: | Reflux of gastric and duodenal contents in patients with gastroesophageal reflux disease (GERD) has been postulated as a major cause of complications, such as Barrett’s esophagus or malignant degeneration. We present a summary of experimental, clinical, and immunohistochemical studies that show that acid and bile reflux are increased in patients who suffer from GERD, are the key factor in the pathogenesis of Barrett’s esophagus, and are possibly related to the development of esophageal adenocarcinoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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