Postobstructive enteropathy in infants with transient enterostomy: Its consequences on the upper small intestinal functions
| Autor: | E. Sonsino, Jean Navarro, G. Weisgerber, J. Macry, Yves Aigrain, Jean Pierre Cezard, N. Lambert, E. Grasset |
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| Rok vydání: | 1992 |
| Předmět: |
Parenteral Nutrition
medicine.medical_specialty Gastroenterology Intestinal absorption Postoperative Complications Recurrence Internal medicine Intestine Small Occlusion medicine Humans Enteropathy business.industry Intestinal atresia Enterostomy Infant Newborn General Medicine medicine.disease Small intestine Intestinal Diseases Parenteral nutrition medicine.anatomical_structure Intestinal Absorption Atresia Pediatrics Perinatology and Child Health Surgery Gastrointestinal Motility Complication business Intestinal Obstruction |
| Zdroj: | Journal of Pediatric Surgery. 27:1427-1432 |
| ISSN: | 0022-3468 |
| DOI: | 10.1016/0022-3468(92)90192-a |
| Popis: | Repeated or prolonged organic obstruction of the small intestine in the neonatal period can lead to severe refeeding problems, despite a transient ostomy. These problems are thought to result from a postobstructive enteropathy (POE) of the apparently normal small intestine segment above the obstruction. Ten infants with a POE, characterized by limited oral caloric and carbohydrate intakes and increased ostomy effluent, were compared with 8 controls with an enterostomy and a normal postoperative refeeding pattern. There was no statistical difference in the histomorphometric appearance of the mucosa or its digestive or absorptive capacity (brush-border hydrolases, glucose transport) between the two groups. The effluent and duodenal floras of the two groups were similar. However, all POE patients showed significant abnormal peristalsis characterized by barium and carmin transit times. This suggests that repeated or prolonged obstruction in the neonatal period could lead to a POE, caused by chronic motricity abnormalities of the small intestine above the obstruction. Although this POE is more frequent after small bowel atresia, it may also occur with other conditions causing prenatal and postnatal intestinal obstruction. |
| Databáze: | OpenAIRE |
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