Pharmacological and chemical properties of some marine echinoderms
| Autor: | Maha El Hamdani, S. Sherif Ebada, My El Abbes Faouzi, Ilias Marmouzi, Yahia Cherrah, Aisha Attar, Rachid Alami, Naoufal Tamsouri, Meryem El Jemli, Mourad Kharbach |
|---|---|
| Přispěvatelé: | Analytical Chemistry and Pharmaceutical Technology, Faculty of Medicine and Pharmacy |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
lcsh:RS1-441 Human pathogen Bacillus subtilis Plant use of endophytic fungi in defense lcsh:Pharmacy and materia medica Pharmacology Toxicology and Pharmaceutics(all) 03 medical and health sciences chemistry.chemical_compound α-Amylase Food science General Pharmacology Toxicology and Pharmaceutics Astropecten irregularis Ophiura albida 030109 nutrition & dietetics biology biology.organism_classification Antimicrobial 030104 developmental biology Phenolic α-Glucosidase Pyrogallol chemistry Salmonella enterica antimicrobial phenolic Echinoderms |
| Zdroj: | Revista Brasileira de Farmacognosia v.28 n.5 2018 Revista Brasileira de Farmacognosia Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA Revista Brasileira de Farmacognosia, Volume: 28, Issue: 5, Pages: 575-581, Published: OCT 2018 Revista Brasileira de Farmacognosia, Vol 28, Iss 5, Pp 575-581 Revista Brasileira de Farmacognosia, Vol 28, Iss 5, Pp 575-581 (2018) |
| ISSN: | 0102-695X |
| Popis: | Echinoderms have attracted the attention of scientists over the past few years after identifying a variety of unique structures endowed by interesting biological properties. However, the Moroccan coast biodiversity is still uninvestigated. In our ongoing attempts to valorize the rich Moroccan marine environment, this study aimed at assessing the antimicrobial activity of extracts obtained from three echinoderms Astropecten irregularis, Luidia sarsi and Ophiura albida against the human pathogens: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica and Bacillus subtilis. Moreover, their antioxidant activities were tested using standard methods in addition to the antidiabetic activity which has been evaluated in vitro against α-amylase and α-glucosidase enzymes. HPLC-DAD-QTOF-MS analysis revealed a significant content of some phenolic compounds such as pyrogallol, gallic, sinapic, ferulic, p-hydroxybenzoic and salicylic acids whose existence can be related to the endophytic fungi and/or dietary intake whereas GC-MS analysis exhibited diverse chemical structures such as cholesterol, oleic acid and glycerol 1-palmitate. Keywords: Echinoderms, Phenolic, α-Amylase, α-Glucosidase, Antimicrobial |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink