Association of pro-inflammatory cytokine gene polymorphisms with schizophrenia in South Indian population
| Autor: | Moinak Banerjee, Lekshmy Srinivas, Priya M Allencherry, N V Neetha, Chandrasekharan M. Nair |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Biochemistry
medical business.industry Biochemistry (medical) Population genetics Disease Bioinformatics Mental illness medicine.disease behavioral disciplines and activities Molecular medicine Biochemistry Human genetics Immune system Schizophrenia mental disorders Poster Presentation Genetics Medicine Molecular Medicine Genetics(clinical) business Gene Molecular Biology Genetics (clinical) |
| Zdroj: | Molecular Cytogenetics |
| ISSN: | 1755-8166 |
| Popis: | Background Schizophrenia is a severe and debilitating mental illness. Around 0.26% of people in South India suffer from schizophrenia. It is a complex disorder which may involve multiple genes with mild to moderate effect and nongenetic risk factors like environmental and psychological assaults. Cytokines, regulators of immune/inflammatory reactions and brain development, emerge as part of a common pathway of genetic and environmental components of schizophrenia. Our study explored the association of polymorphisms in cytokine genes with schizophrenia, the interaction of these genes in the causation of the disease and the population genetics of cytokine gene polymorphisms. |
| Databáze: | OpenAIRE |
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