Sympathetic vasoconstrictor responses in multiple sclerosis with thermoregulatory dysfunction
| Autor: | E. B. Andersen, A. M. Nordenbo |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty Multiple Sclerosis Sympathetic Nervous System Neurology Sweating Diabetes mellitus Internal medicine medicine Humans Muscle Skeletal integumentary system Vasomotor Endocrine and Autonomic Systems business.industry Multiple sclerosis Skeletal muscle Middle Aged medicine.disease Sudomotor Endocrinology medicine.anatomical_structure Regional Blood Flow Vasoconstriction cardiovascular system Reflex Female Neurology (clinical) business Body Temperature Regulation circulatory and respiratory physiology Subcutaneous tissue |
| Zdroj: | Clinical Autonomic Research. 7:13-16 |
| ISSN: | 1619-1560 0959-9851 |
| DOI: | 10.1007/bf02267621 |
| Popis: | Centrally and locally mediated sympathetic vasoconstrictor responses in skeletal muscle and subcutaneous tissue were studied in six patients with definite multiple sclerosis and severely affected thermoregulatory sweating. The purpose of the study was to evaluate vasomotor function in patients with pronounced thermoregulatory dysfunction and to differentiate between locally and centrally elicited vasomotor reflexes in two different tissues. The method used, the 133-Xenon washout technique, makes such a distinction possible. In spite of the severe sweating disturbances, we found centrally and locally mediated sympathetic vasomotor reflexes to be preserved in skeletal muscle and subcutaneous tissue. The results support the view that sudomotor and vasomotor functions are independently controlled. Previously described differences in sympathetic vasoconstrictor responses in skeletal muscle and subcutaneous tissue in several other neurological disorders are not present in patients with multiple sclerosis, based on our results. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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