Acute Kidney Injury in Critically Ill Children Is Not all Acute: Lessons Over the Last 5 Years
| Autor: | Catherine Morgan, Rashid Alobaidi, Emma Ulrich, Erin Hessey, Manish D. Sinha, Sean M. Bagshaw, Nabil Melhem |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
hypertension Population 030232 urology & nephrology Review 030204 cardiovascular system & hematology urologic and male genital diseases Pediatrics 03 medical and health sciences 0302 clinical medicine medicine Risk factor Intensive care medicine education Pediatric intensive care unit education.field_of_study Proteinuria business.industry urogenital system Acute kidney injury lcsh:RJ1-570 healthcare utilization lcsh:Pediatrics medicine.disease mortality Cardiac surgery critical care acute kideny injury Healthcare utilization Pediatrics Perinatology and Child Health medicine.symptom business long-term follow up chronic kidney disease Kidney disease |
| Zdroj: | Frontiers in Pediatrics, Vol 9 (2021) Frontiers in Pediatrics |
| ISSN: | 2296-2360 |
| DOI: | 10.3389/fped.2021.648587/full |
| Popis: | Acute kidney injury (AKI) in the pediatric intensive care unit (PICU) is an important risk factor for increased morbidity and mortality during hospitalization. Over the past decade, accumulated data on children and young people indicates that acute episodes of kidney dysfunction can have lasting consequences on multiple organ systems and health outcomes. To date, there are no guidelines for follow-up of surviving children that may be at risk of long-term sequelae following AKI in the PICU. This narrative review aims to describe literature from the last 5 years on the risk of medium and long-term kidney and non-kidney outcomes after AKI in the PICU. More specifically, we will focus on outcomes in children and young people following AKI in the general PICU population and children undergoing cardiac surgery. These outcomes include mortality, hypertension, proteinuria, chronic kidney disease, and healthcare utilization. We also aim to highlight current gaps in knowledge in medium and long-term outcomes in this pediatric population. We suggest a framework for future research to develop evidence-based guidelines for follow-up of children surviving an episode of critical illness and AKI. |
| Databáze: | OpenAIRE |
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