Surface-enhanced Raman scattering tags for rapid and homogeneous detection of circulating tumor cells in the presence of human whole blood

Autor:	Michael Y. Sha, Hongxia Xu, Michael J. Natan, Remy Cromer
Rok vydání:	2008
Předmět:	Surface Properties Cell Analytical chemistry Apoptosis Spectrum Analysis Raman Biochemistry Models Biological Catalysis Article Cell Line chemistry.chemical_compound Magnetics Colloid and Surface Chemistry Circulating tumor cell Antigen Microscopy Electron Transmission Antigens Neoplasm medicine Humans Scattering Radiation Whole blood biology Dose-Response Relationship Drug Cell adhesion molecule Epithelial cell adhesion molecule General Chemistry Epithelial Cell Adhesion Molecule Neoplastic Cells Circulating medicine.anatomical_structure Blood chemistry Cell culture biology.protein Biophysics Antibody Cell Adhesion Molecules Signal Transduction
Zdroj:	Journal of the American Chemical Society. 130(51)
ISSN:	1520-5126
Popis:	A novel, homogeneous SERS-based cell detection assay was developed for rapid and direct enumeration of circulating tumor cells in the presence of whole blood. Magnetic beads and SERS tags were respectively conjugated to EpCAM and her2 antibodies for the capture and detection of approximately 50 tumor cells/mL in the presence of whole blood in less than 1 h.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853cc38ff18ac4a91e1a2de6911af116 https://pubmed.ncbi.nlm.nih.gov/19053187 Zobrazit plný text záznamu