Protoaculeine B, a Putative N-Terminal Residue for the Novel Peptide Toxin Aculeines
| Autor: | Masaki J. Fujita, Satoko Matsunaga, Kazunori Otsuka, Masato Oikawa, Reimi Kishi, Ryuichi Sakai |
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| Rok vydání: | 2014 |
| Předmět: |
Indoles
Magnetic Resonance Spectroscopy Stereochemistry Protoaculeine B Peptide medicine.disease_cause Biochemistry chemistry.chemical_compound Polyamines medicine Animals Physical and Theoretical Chemistry Indole test chemistry.chemical_classification Molecular Structure biology Toxin Organic Chemistry biology.organism_classification Porifera Amino acid Sponge chemistry Terminal residue Peptides Derivative (chemistry) |
| Zdroj: | Organic Letters. 16:3090-3093 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | A new polyamine-modified indole derivative protoaculeine B (1) was isolated from Okinawan marine sponge Axinyssa aculeata. The structure of 1 was assigned on the basis of spectral data along with chemical transformations. Because the structure of 1 greatly inferred the N-terminal amino acid for highly modified peptide toxin aculeines, the probable structure for aculeine B was proposed on the basis of high-resolution mass spectral analysis. |
| Databáze: | OpenAIRE |
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