The Natural history of Epicardial Adipose Tissue Volume and Attenuation: A long-term prospective cohort follow-up study

Autor:	Rahul G. Muthalaly, Nitesh Nerlekar, Damini Dey, Elizabeth L. Potter, Ji Quan Samuel Koh, Hashrul Rashid, James D. Cameron, David Liu, Dennis T.L. Wong, Andrew Lin, Udit Thakur
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Male medicine.medical_specialty Computed Tomography Angiography Cardiology lcsh:Medicine Coronary Artery Disease Disease 030204 cardiovascular system & hematology Coronary Angiography Article Body Mass Index 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences 0302 clinical medicine Internal medicine Hounsfield scale Diabetes mellitus medicine Humans Prospective Studies Registries Prospective cohort study lcsh:Science Coronary atherosclerosis Aged Retrospective Studies Multidisciplinary business.industry lcsh:R Middle Aged medicine.disease Natural history Adipose Tissue Hypertension Female lcsh:Q Angiogenesis business Pericardium Body mass index Follow-Up Studies
Zdroj:	Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020) Scientific Reports
ISSN:	2045-2322
Popis:	Epicardial adipose tissue (EAT) is associated with cardiovascular risk. The longitudinal change in EAT volume (EATv) and density (EATd), and potential modulators of these parameters, has not been described. We prospectively recruited 90 patients with non-obstructive coronary atherosclerosis on baseline computed tomography coronary angiography (CTCA) performed for suspected coronary artery disease to undergo a repeat research CTCA. EATv in millilitres (mL) and EATd in Hounsfield units (HU) were analysed and multivariable regression analysis controlling for traditional cardiovascular risk factors (CVRF) performed to assess for any predictors of change. Secondary analysis was performed based on statin therapy. The median duration between CTCA was 4.3years. Mean EATv increased at follow-up (72 ± 33 mL to 89 ± 43 mL, p
Databáze:	OpenAIRE
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