Cervical cancer prevention among older women - challenges in screening, diagnostic workup, and treatment
Autor: | Line Winther Gustafson, Pinar Bor, Berit Andersen, Anne Hammer, Lone Kjeld Petersen |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Pediatrics
cervical cancer screening Uterine Cervical Neoplasms 0302 clinical medicine older women 030212 general & internal medicine Practice Patterns Physicians' human papillomavirus RISK Cervical cancer Colposcopy Aged 80 and over postmenopausal 030219 obstetrics & reproductive medicine medicine.diagnostic_test Incidence (epidemiology) Mortality rate colposcopy Age Factors Obstetrics and Gynecology General Medicine Cervical Cancer prevention Women's Health Services medicine.anatomical_structure Female medicine.medical_specialty high-risk HPV cervical intraepithelial neoplasia Cervical intraepithelial neoplasia EXCISION 03 medical and health sciences Uterine Cervical Neoplasms/prevention & control medicine Humans Cervix Aged Vaginal Smears business.industry screening Cervical Intraepithelial Neoplasia/prevention & control medicine.disease Uterine Cervical Dysplasia INTRAEPITHELIAL NEOPLASIA Gynecology Cervical cancer prevention PATTERNS business Cervical cancer incidence |
Zdroj: | Gustafson, L W, Kjeld Petersen, L, Bor, I P, Andersen, B & Hammer, A 2021, ' Cervical cancer prevention among older women-challenges in screening, diagnostic workup, and treatment ', Acta Obstetricia et Gynecologica Scandinavica (AOGS) . https://doi.org/10.1111/aogs.14162 Gustafson, L W, Petersen, L K, Bor, I P, Andersen, B & Hammer, A 2021, ' Cervical cancer prevention among older women-challenges in screening, diagnostic workup, and treatment ', Acta Obstetricia et Gynecologica Scandinavica, vol. 100, no. 8, pp. 1364-1368 . https://doi.org/10.1111/aogs.14162 Gustafson, L W, Petersen, L K, Bor, P, Andersen, B & Hammer, A 2021, ' Cervical cancer prevention among older women – challenges in screening, diagnostic workup and treatment ', Acta Obstetricia et Gynecologica Scandinavica, vol. 100, no. 8, pp. 1364-1368 . https://doi.org/10.1111/aogs.14162 |
DOI: | 10.1111/aogs.14162 |
Popis: | Cervical cancer incidence and mortality have declined dramatically after screening for cervical cancer was implemented. Yet, studies have reported high cervical cancer incidence and mortality rates at older age despite low HPV prevalence and incidence of precursor lesions. The underlying reason for these findings remains unclear. However, it is well known that the impact of screening depends not only on the uptake and effectiveness of screening but also on the uptake and effectiveness of diagnostic workup (ie colposcopy), treatment and follow-up. In older women, sensitivity of screening and performance of colposcopy are impaired due to age-dependent changes to the cervix. In this commentary, we aimed to discuss challenges in screening and clinical management of older women, and to identify crucial areas of particular interest for future research. |
Databáze: | OpenAIRE |
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