Stage-related correlations between immunoglobulins and complement components in preoperative sera from patients with gastric carcinoma
| Autor: | Janssen Cw, Roald Matre, Tønder O |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Immunoglobulins Gastric carcinoma Biology Complement C1 Inactivator Proteins Positive correlation Complement components Preoperative staging Stomach Neoplasms Carcinoma medicine Humans Longitudinal Studies Stage (cooking) Aged Neoplasm Staging Complement C4 Complement C3 Complement System Proteins Middle Aged medicine.disease Immunoglobulin A Oncology Immunoglobulin M Immunoglobulin G biology.protein Female Antibody Stage iv |
| Zdroj: | European journal of cancerclinical oncology. 19(11) |
| ISSN: | 0277-5379 |
| Popis: | Immunoglobulins A, G and M and complement components C3, C4 and C1-INH were quantitated in sera taken preoperatively from 168 patients with gastric carcinoma. The values were grouped according to stages (pTNM). The concentrations of C4 and C1-INH increased with advancing stage of disease and were above normal mean values in all stages. The concentration of IgG was below the normal mean value among all the patients and with the lowest concentration in stage III. Concentrations of IgA and C3 were above normal means but without significant relation to stages. There was a positive correlation between the concentrations of IgG and C1-INH in sera from patients with stage IV carcinoma, while the same correlation was negative in stages I-III. Although the results varied among the patients within each stage, the profiles of immunoglobulin and complement concentrations are of value in the preoperative staging of the disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|