A Pilot Study Comparing Aortic Valve Area Estimates Derived from Fick Cardiac Output with Estimates Based on Cheetah-NICOM Cardiac Output
| Autor: | Kinjal M. Patel, Vineeth Nagubandi, Janah Aji, Zahi Rafeq, Jeffrey Ogbara, John P. Gaughan, Debbie Orr, Noud van Helmond, Michael Rosenbloom, Georges Kaddissi, Ahmed Awad, Ludmil Mitrev |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Cardiac output medicine.medical_treatment Cardiology lcsh:Medicine Pilot Projects Fick method 030204 cardiovascular system & hematology Article Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology Internal medicine medicine Humans In patient Cardiac Output lcsh:Science Cardiac catheterization Aged Aged 80 and over Multidisciplinary business.industry Limits of agreement lcsh:R Middle Aged medicine.disease Confidence interval Stenosis Aortic valve area Aortic Valve lcsh:Q Female business Interventional cardiology |
| Zdroj: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020) Scientific Reports, 10, 1 Scientific Reports, 10 |
| ISSN: | 2045-2322 |
| Popis: | Cardiac output during cardiac catheterization is often estimated using the modified Fick method (COFick). In this proof-of-concept, prospective non-randomized study carried out in a single academic healthcare centre, we examined whether replacing COFick in the Gorlin formula with Cheetah-NICOM monitor cardiac output (COCheetah) could produce an accurate and precise estimate of aortic valve area in patients with severe aortic stenosis. In twenty-six subjects, COFick and COCheetah were obtained concurrently. A spot and 3-minute running average of COCheetah was used. Bland and Altman analysis was used to derive bias, 95% limits of agreement (LOA) and confidence intervals (CI). The mean difference (bias) between AVACheetah (average) and AVAFick was 0.11 cm2 and the 95% LOA were ±0.42 cm2. The 95% CI of the bias was 0.02–0.2 cm2. The bias and 95% LOA of AVACheetah (spot value) were 0.14 ± 0.42cm2, with a 95% CI of 0.06–0.23 cm2. No proportional bias was present. AVACheetah thus appears to be a reasonably accurate measure of AVA in patients with severe aortic stenosis compared to AVAFick measured using a modified Fick CO. However, the limits of agreement were not narrow enough to consider AVACheetah and AVAFick interchangeable. |
| Databáze: | OpenAIRE |
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