Serological diagnosis of acute viral hepatitis
| Autor: | J G Waggoner, Leonard B. Seeff, Antonio Ponzetto, L R Mathiesen, Z B Bales, Jay H. Hoofnagle |
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| Rok vydání: | 1985 |
| Předmět: |
Adult
Male Herpesvirus 4 Human Immunodiffusion HBsAg Hepatitis Viral Human Physiology viruses Radioimmunoassay Enzyme-Linked Immunosorbent Assay Antibodies Viral medicine.disease_cause medicine Humans Hepatitis B Antibodies Hepatitis Hepatitis B virus Hepatitis B Surface Antigens business.industry Gastroenterology Hepatitis A Hepatitis C Hepatitis B medicine.disease Hepatitis B Core Antigens Virology Hepatitis D Immunoglobulin M Immunology Female Viral hepatitis business |
| Zdroj: | Digestive Diseases and Sciences. 30:1022-1027 |
| ISSN: | 1573-2568 0163-2116 |
| Popis: | Fifty cases of symptomatic acute viral hepatitis presenting at the Washington, D.C., Veterans Administration Medical Center between 1976 and 1978 were tested for serological markers of hepatitis virus infection. The etiology of the acute hepatitis appeared to be hepatitis A virus in 20%, hepatitis B virus in 52%, non-A, non-B agents in 22%, delta hepatitis in 4%, and infectious mononucleosis in 2%. The diagnosis of type B hepatitis was difficult to verify because 10% of cases were seronegative for HBsAg and another 10% were seronegative by conventional testing for IgM antibody to hepatitis B core antigen (a putative marker of acute hepatitis B virus infection). Accurate serodiagnosis of acute viral hepatitis depends upon the correct application of testing for IgM antibody to hepatitis A virus, IgM antibody to hepatitis B core antigen, HBsAg, and tests for syphilis and mononucleosis. |
| Databáze: | OpenAIRE |
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