Mild synthesis of [N-methyl-11C]-isovaleroyl-(L)-carnitine. The usefulness of a tritium approach

Autor:	F. Fazio, F. Carnevaletti, S. Todde, G. Corsi, O. Tinti, A. Margonelli, Giancarlo Angelini, P. Ragni
Přispěvatelé:	Angelini, G, Carnevaletti, F, Margonelli, A, Corsi, G, Ragni, P, Fazio, F, Todde, S, Tinti, O
Jazyk:	angličtina
Rok vydání:	1999
Předmět:	chemistry.chemical_compound Radiation chemistry Radiosynthesis medicine Organic chemistry Tritium Carnitine [N-methyl-11C]-isovaleroyl-(L)-carnitine Derivative (chemistry) Methyl iodide medicine.drug
Popis:	The title carnitine derivative was labelled both with [11C]methyl iodide and [3H]methyl iodide. The former was synthesized in order to improve the knowledge of the acyl carnitines fate in humans. The latter was synthesized, at approximately the same concentration level as that of the former, in order to optimize its radiosynthesis, taking advantage from the long half-life of the tritium. # 1999 Elsevier Science Ltd. All rights reserved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85071637f9ed873ce1386e34892b365d http://hdl.handle.net/10281/17405 Zobrazit plný text záznamu