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Background: Nanoparticles play a very important role in our daily lives and have a wide range of applications in agriculture and biology, such as antioxidants and antimicrobial compounds. Among them are gold nanoparticles (AuNPs) that are highly complex and are widely used. In recent years gold nanoparticles have attracted much attention because of their optical properties, electron-ic, physicochemical, and surface Plasmon resonance (SPR). Gold plated nanoparticles, similar to metal nanoparticles, have many unusual chemical and physical properties due to the effects of their quantum size and location compared to other iron or metal atoms. Gold nanoparticles can be used in pharmaceutical products such as antimicrobial and anti-biofilm agents, targeted delivery of anti-cancer drugs, biosensors, biocatalysis, bioremediation modification of toxic chemicals exposing the soil and atmosphere, dye reduction, etc. Yet such methods are expensive and out of harmony with nature. In that account, the microbes-mediated synthesis of gold nanoparticles recently changed rap-idly when pure microbes becoming ac-friendly, non-toxic, and biocompatible as physiological and chemical methods. This document aims to review the progress made in recent years with the fusion of gold nanoparticles. The microbial source includes bacteria, algae fungi. These works motivate people how to apply and synthesize gold nanoparticles. This review also focuses on the process of classification of gold nanoparticles, structures, and their use in the development of various require-ments. Objective: The main goal is to study gold nanoparticles and their application in the future. Methods: We studied different research papers, reviewed papers from “Google Scholar”, “NCBI”, “PubMed”, “Science Direct” made. Conclusion: Metal nanoparticles are Conclusion: Metal nanoparticles are suitable for many emerging technologies. Understanding the microorganisms found in nature because the fusion of gold nanoparticles is required. |