The intraspecific variability of mitochondrial genes of Agaricus bisporus reveals an extensive group I intron mobility combined with low nucleotide substitution rates
| Autor: | Banafsheh Jalalzadeh, Philippe Callac, Jean-Michel Savoie, Cyril Férandon, Mohammad Farsi, Gérard Barroso, Idy Carras Sare |
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| Přispěvatelé: | Unité de recherche Mycologie et Sécurité des Aliments (MycSA), Institut National de la Recherche Agronomique (INRA) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Mitochondrial DNA
Agaricus RNA Splicing [SDV]Life Sciences [q-bio] Molecular Sequence Data Polymorphism Single Nucleotide Homing endonuclease Intraspecific competition Evolution Molecular Intergenic region Mutation Rate Gene Order Genetics Group I catalytic intron Gene Phylogeny biology Base Sequence Intron Genetic Variation General Medicine Introns Genes Mitochondrial biology.protein Nucleic Acid Conformation Agaricus bisporus |
| Zdroj: | Current Genetics Current Genetics, Springer Verlag, 2015, 61 (1), pp.87-102. ⟨10.1007/s00294-014-0448-8⟩ |
| ISSN: | 0172-8083 1432-0983 |
| DOI: | 10.1007/s00294-014-0448-8⟩ |
| Popis: | International audience; Intraspecific mitochondrial variability was studied in ten strains of A. bisporus var. bisporus, in a strain representative of A. bisporus var. eurotetrasporus and in a strain of the closely related species Agaricus devoniensis. In A. bisporus, the cox1 gene is the richest in group I introns harboring homing endonuclease genes (heg). This study led to identify group I introns as the main source of cox1 gene polymorphism. Among the studied introns, two groups were distinguished according to the heg they contained. One group harbored heg maintained putatively functional. The other group was composed of eroded heg sequences that appeared to evolve toward their elimination. Low nucleotide substitution rates were found in both types of intronic sequences. This feature was also shared by all types of studied mitochondrial sequences, not only intronic but also genic and intergenic ones, when compared with nuclear sequences. Hence, the intraspecific evolution of A. bisporus mitochondrial genome appears characterized by both an important mobility (presence/absence) of large group I introns and by low nt substitution rates. This stringent conservation of mitochondrial sequences, when compared with their nuclear counterparts, appears irrespective of their apparent functionality and contrasts to what is widely accepted in fungal sequence evolution. This strengthens the usefulness of mtDNA sequences to get clues on intraspecific evolution. |
| Databáze: | OpenAIRE |
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