Comparison Between Gleason Score and Apparent Diffusion Coefficient Obtained from Diffusion-Weighted Imaging of Prostate Cancer Patients
| Autor: | Marco Salvatore, Rocchina Caivano, Antonella Lotumolo, Luca Macarini, Aldo Cammarota, Antonio Villonio, Paola Rabasco, Alexis Zandolino, Felice D'Antuono, Patrizia Cirillo |
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| Přispěvatelé: | Rocchina, Caivano, Paola, Rabasco, Antonella, Lotumolo, Patrizia, Cirillo, Felice, D'Antuono, Alexis, Zandolino, Antonio, Villonio, Luca, Macarini, Salvatore, Marco, Aldo, Cammarota |
| Rok vydání: | 2013 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Biopsy Prostate cancer Predictive Value of Tests Humans Medicine Effective diffusion coefficient Gleason scores Pathological Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry Prostatic Neoplasms Magnetic resonance imaging General Medicine Prostate carcinoma Middle Aged Prognosis medicine.disease body regions Diffusion Magnetic Resonance Imaging Oncology Radiology Neoplasm Grading business Nuclear medicine Diffusion MRI |
| Popis: | Objectives: To correlate the apparent diffusion coefficient (ADC) of prostate cancer patients with pathological Gleason scores (GS). Methods: 40 patients with GS 2 + 3, 3 + 3, 3 + 4, or 4 + 4 were selected. The magnetic resonance imaging (MRI) study was performed adding axial diffusion-weighted imaging (DWI) sequences to the standard MRI protocol. ADC values obtained were correlated with the GS data. Results: Statistically significant differences of ADC (p < .05) were found among GS groups with a trend of decreasing ADC values with increasing GS. Conclusions: The ADC values may help clinicians to delineate prostate carcinoma, recognizing its high- or low-grade compartments. |
| Databáze: | OpenAIRE |
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