Characterization of PMMA-b-PDMAEMA aggregates in aqueous solutions
| Autor: | Greice Kelle Viegas Saraiva, J. C. Masini, L. Coutinho de Oliveira, V. V. de Souza, Hernan Chaimovich, Fabio Herbst Florenzano, Roberto Kopke Salinas, Iolanda M. Cuccovia, M. L. C. Noronha |
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| Přispěvatelé: | Universidade de São Paulo (USP), Institut Armand Frappier (INRS-IAF), Institut National de la Recherche Scientifique [Québec] (INRS)-Réseau International des Instituts Pasteur (RIIP), Universidade Federal de Alfenas (UNIFAL), Centro Universitário de Itajubá (FEPI), FAPESP (grant number 2013/08166-5 and 2016/07490-1). IMC has been supported by the INCT-FCx (Instituto Nacional de Ciência e Tecnologia de Fluidos Complexos (CNPq/CAPES/FINEP/FAPESP) and NAP-FCx (Núcleo de Apoio à Pesquisa de Fluidos Complexos da Universidade de São Paulo)., IMC, HC, and RKS are CNPq research scholars. GKVS acknowledges the Projeto Biocomputacional/CAPES (proc. no. 23038.004630/2014-35) and CNPq (proc. 457733/2014-4). |
| Rok vydání: | 2019 |
| Předmět: |
Polymers and Plastics
[SDV]Life Sciences [q-bio] Magnetic resonance: NMR/ESR Protonation 02 engineering and technology 010402 general chemistry Methacrylate 01 natural sciences chemistry.chemical_compound Colloid and Surface Chemistry Polymer chemistry Materials Chemistry Copolymer Reversible addition−fragmentation chain-transfer polymerization Physical and Theoretical Chemistry Methyl methacrylate Spectroscopy chemistry.chemical_classification Aqueous solution Responsive systems Copolymers Polymer Nuclear magnetic resonance spectroscopy 021001 nanoscience & nanotechnology ESPECTROSCOPIA 0104 chemical sciences chemistry Polymer solutions Polymer synthesis 0210 nano-technology |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP Colloid and Polymer Science Colloid and Polymer Science, Springer Verlag, 2019, 297 (4), pp.557-569. ⟨10.1007/s00396-019-04482-w⟩ |
| ISSN: | 0303-402X 1435-1536 |
| DOI: | 10.1007/s00396-019-04482-w⟩ |
| Popis: | International audience; Diblock amphiphilic copolymers form aggregates in some solvents. Such aggregates exhibit different morphologies, depending mainly on the polar/apolar block ratios. Aggregation of copolymers with polar block excess leads to micelle-like aggregates, known as polymeric micelles, which can be used as vehicles for drug and gene delivery, water decontamination, and catalysis. Here, we synthesized by RAFT polymerization three different polymers namely [dimethyl 2-(aminoethyl) methacrylate] (PDMAEMA), poly (methyl methacrylate) (PMMA) copolymers, and PDMAEMA-block-PMMA and characterized their aggregates by NMR spectroscopy and pH titrations. We investigated correlations between their chemical structure, aggregation behavior, protonation degree, and chain conformation in the corona. Decreased amine protonation in the copolymers reduced the electrostatic repulsion, and the apparent pKa of the amino groups approached that of isolated amine. These effects increased compactness and sizes of the polymers and their aggregates at higher pH as reflected by the increased NMR line widths. |
| Databáze: | OpenAIRE |
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