Factors associated with the number and size of renal angiomyolipomas in sporadic angiomyolipoma (sAML): a study of adult patients with sAML managed in a Dutch tertiary referral center
| Autor: | Raluca Ionescu-Ittu, Matthew Magestro, Bernard A. Zonnenberg, Francis Vekeman, Paul Karner, Jonathan Fortier, Mei Sheng Duh, Maureen P. Neary, J.L.H. Ruud Bosch |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Nephrology
Adult Male medicine.medical_specialty Pediatrics Angiomyolipoma Urology medicine.medical_treatment 030232 urology & nephrology Renal function Hemorrhage Nephrectomy Neoplasms Multiple Primary Tertiary Care Centers 03 medical and health sciences Tuberous sclerosis 0302 clinical medicine Kidney function Internal medicine medicine Humans Stage (cooking) Young adult Renal Insufficiency Chronic Aged Netherlands Retrospective Studies Ultrasonography Disease monitoring Urology - Original Paper business.industry Age Factors Middle Aged medicine.disease Embolization Therapeutic Kidney Neoplasms Tumor Burden Treatment 030220 oncology & carcinogenesis Hypertension Female business Tomography X-Ray Computed Kidney disease Glomerular Filtration Rate |
| Zdroj: | International Urology and Nephrology |
| ISSN: | 1573-2584 0301-1623 |
| Popis: | Purpose To describe the patient characteristics, treatments, disease monitoring, and kidney function of patients with sporadic angiomyolipoma (sAML), stratified by the number and size of renal angiomyolipomas (AMLs). Methods Single-center retrospective analysis of patients with sAML treated from 1990 to 2015 in a dedicated clinic for inheritable tumor syndromes in a tertiary referral center from the Netherlands. Patients’ first AML assessment at the clinic was defined as the index date. Patient characteristics were measured at the index date. Treatments, disease monitoring, and kidney function were measured post-index date. Results The study sample included 53 patients followed for a total of 184.6 patient-years. At the index date, the largest AML was ≥ 3.5 cm for 26 patients and |
| Databáze: | OpenAIRE |
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